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Open Access Article

Journal of Agriculture and Food Science. 2026; 6: (1) ; 20-25 ; DOI: 10.12208/j.jafs.20260004.

Research progress on the application of fermented traditional Chinese medicine in veterinary clinical practice
中药发酵在兽医临床中的应用研究进展

作者: 邹兴芬 *

广安市广安区大龙镇畜牧兽医站 四川广安;

*通讯作者: 邹兴芬,单位:广安市广安区大龙镇畜牧兽医站 四川广安; ;

发布时间: 2026-05-18 总浏览量: 128

摘要

中药饲料添加剂在现代畜牧生产中应用广泛,但常规散剂与粉剂因纤维含量高、细胞壁结构稳定,使得活性成分难以有效释放。微生物发酵可通过仿生消化机制,利用菌株分泌的纤维素酶、半纤维素酶、果胶酶等降解细胞壁屏障,促进苷类、多糖、有机酸等物质的溶出与转化。研究表明,发酵处理可使中药药效增强4~28倍,产品具有吸收效率高、作用显著、不良反应少等优势。但是目前发酵中药存在工艺参数缺乏统一标准、药效物质基础与作用机制研究不足、没有标准统一的质量评价体系以及缺乏大规模的临床验证数据。迫切需要构建精细化、标准化的质控监管体系,深入研究发酵过程中的物质相互作用规律,并开展规范的临床验证试验,用以支撑发酵中药在畜牧养殖业的精准化、规模化应用。本文将系统综述中药发酵技术的原理、优势,并总结其在猪、禽等畜禽养殖中的临床应用情况,为发酵中药的深入研究与产业化应用提供理论参考。

关键词: 发酵中药;生物转化;生产性能;抗生素替代;畜禽养殖

Abstract

Chinese herbal feed additives are widely used in modern livestock production. However, conventional granular and powdered forms, due to their high fiber content and stable cell wall structure, make it difficult for active components to be effectively released. Microbial fermentation can simulate the digestive mechanism, using enzymes such as cellulase, hemicellulase, and pectinase secreted by strains to degrade the cell wall barrier, promoting the dissolution and transformation of substances like glycosides, polysaccharides, and organic acids. Studies have shown that fermentation treatment can enhance the efficacy of Chinese herbs by 4 to 28 times, and the products have advantages such as high absorption efficiency, significant effects, and few adverse reactions. Fermented traditional Chinese medicine currently faces several fundamental constraints: the absence of standardized process parameters, inadequate elucidation of pharmacodynamic material basis and underlying mechanisms, lack of harmonized quality evaluation frameworks, and insufficient large-scale clinical validation data. To address these limitations, it is imperative to establish refined, standardized quality control and regulatory systems, systematically investigate the interactive dynamics of substances during fermentation processes, and conduct rigorously designed clinical validation studies. These endeavors are critical to enabling the precise, scalable application of fermented traditional Chinese medicine in livestock and poultry production. This review comprehensively examines the mechanistic principles and comparative advantages of fermented traditional Chinese medicine technology, synthesizes available clinical evidence from pig and poultry farming applications, and aims to establish a theoretical foundation to advance both fundamental research and industrial translation of fermented traditional Chinese medicine.

Key words: Fermented traditional Chinese medicine; Biotransformation; Production performance; Antibiotic alternative; Livestock and poultry farming

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引用本文

邹兴芬, 中药发酵在兽医临床中的应用研究进展[J]. 农业与食品科学, 2026; 6: (1) : 20-25.